Hebei Mujin Biotechnology Co.,Ltd
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Country: 
China (Mainland)
Business Type:Trading Company
Tel: 13231137666
Tel: 15028179902
Tel: 13383610321
Tel: +86 13288715578
Tel: +86 13288715308
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Tel: +86 13315458396
Tel: 15103291926
Tel: 13315457394
Mobile: 13231137666
Tel: 13231137666
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Province/state: Hebei
City: shijiazhuang
Street: room 1401,A building,Enjoy city,shijiazhuang city,hebei province,China
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Ms.betty Ms.mayCAS NO.118-48-9
comestic(1-22)Kilogram
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
1. Rich experience.Having been specialized in this field for years, we have rich experience and widespread sales network around the word. Our hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. We are not got good feedback from our guest, but also established long business relationship with them.
2. Great quality and high purity.Good quality is one secret for our success. All of our products enjoys high purity. Thus, it can make sure our client's need. Welcome order the samples, MOQ just 10 grams.
3. Safest and fastest delivery.We have mass stock, so that we can arrange the delivery within 24hours once receiving the payment. Tracking number would be informed quickly after shipment. We have our own way of packing which could ship 0.01 kilo to 50 kilo products a time.
4. Good after-sales service.24/7 is available. We will tell you the package updated info ASAP. And try our best to solve various problems customers encountered!
5. Experiential shopping
Our Advantages
1.Own chemical factory
2.Abundant professional production experience
3.Sample is free of charge and in stock with fast delivery
4. Price,quality & service, we care that all you cares
5. Prompt reply keep in touch to save your times
6.Easily customs clearance, we're very good to all these controls
7.Dedicated researchers to make your customization.
Product details
| CAS: | 118-48-9 |
| MF: | C8H5NO3 |
| MW: | 163.13 |
| EINECS: | 204-255-0 |
| Product Categories: | Pharmaceutical Intermediates;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;pharmacetical;118-48-9 |
| Mol File: | 118-48-9.mol |
| Isatoic Anhydride Chemical Properties |
| Melting point | 233 °C (dec.) (lit.) |
| Boiling point | 290.19°C (rough estimate) |
| density | 1,52 g/cm3 |
| vapor density | 5.6 (vs air) |
| refractive index | 1.5510 (estimate) |
| Fp | 308 °C |
| storage temp. | Store below +30°C. |
| solubility | 0.3g/l |
| pka | 11.06±0.20(Predicted) |
| form | Powder |
| color | Beige to brown |
| Water Solubility | decomposes |
| Sensitive | Moisture Sensitive |
| BRN | 136786 |
| LogP | 0.978 (est) |
| CAS DataBase Reference | 118-48-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Isatoic anhydride(118-48-9) |
| EPA Substance Registry System | 2H-3,1-Benzoxazine-2,4(1H)-dione (118-48-9) |
| Isatoic Anhydride Usage And Synthesis |
| Synthesis | Isatoic Anhydride is synthesized from indole (9a) by stirring in a 4:1 mixture of DMF/H2O for 16 h at room temperature. 1 H NMR (DMSO-d6): δ11.73 (s, br., 1H), 7.92 (d, J = 7.8 Hz, 1H), 7.74 (t, J = 7.8 Hz, 1H), 7.26 (t, J = 7.8 Hz, 1H), 7.16 (d, J = 7.8 Hz, 1H). |
| Chemical Properties | BEIGE TO BROWN POWDER |
| Uses | Isatoic anhydride is a potent inactivator of α-chymotrypsin and inactivates stoichiometrically. Isatoic Anhydride is an important compound in the preparation of serine protease inhibitors. |
| Definition | A bicyclic molecule composed of a benzene ring attached at the oand mpositions to a heterocyclic ring. It forms useful anthranilic acid derivatives by reaction with hydrogen. |
| Preparation | Phosphorus tribromide (0.035 mol) was added to a solution of N-carbethoxy- or N-carbobenzoxy-anthranilic acid (0.1 mol;prepared by coupling anthranilic acid with the corresponding carbalkoxy chloride in the usual way) in anhydrous diethyl ether (100 mL). After 24 h at room temperature, isatoic anhydride had separated as a microcrystalline product. It was collected by filtration, washed with dry diethyl ether, and recrystallized from ethanol. Yield ca. 90%. |
| Flammability and Explosibility | Non flammable |
| Purification Methods | Recrystallise it from EtOH or 95% EtOH (30mL/g) or dioxane (10mL/g) and dry it in a vacuum. [Wagner & Fegley Org Synth Coll Vol III 488 1955, Ben-Ishai & Katchalski J Am Chem Soc 74 3688 1952, UV: Zentmyer & Wagner J Org Chem 14 967 1949, Beilstein 27 II 299, 27III/IV 3330.] |
Product usage
Isatoic anhydride is a potent inactivator of α-chymotrypsin and inactivates stoichiometrically. Isatoic Anhydride is an important compound in the preparation of serine protease inhibitors. |
Company profile
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises.Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
