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CAS NO.161796-78-7
comestic(25-100)Kiloliter
Hebei Mojin Biotechnology Co., Ltd,Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
Adenosine triphosphate can be used in the disease caused by tissue injury and activity reduction of ecto enzyme , including heart failure, carditis, miocardial infarction, cerebral arteriosclersis, coronary sclerosis, progressive muscular atrophy , cerebral hemorrhage , chronic hepatitis, cirrhosis of liver and hearing handicap, etc.
Product Detailed
Name | Esomeprazole sodium | |
Synonyms | 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt | |
Molecular Structure | ||
Molecular Formula | C17H20N3NaO3S | |
Molecular Weight | 369.41 | |
CAS Registry Number | 161796-78-7 |
Esomeprazole is in a group of drugs called proton pump inhibitors. Esomeprazole decreases the amount of acid produced in the stomach.
Esomeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Esomeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Esomeprazole sodium is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.IC50 value:Target: proton pumpEsomeprazole sodium (Nexium) is the S-isomer of omeprazole and acts as a proton pump inhibitor and gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis. Esomeprazole 0.4 and 0.8 mg/mL as the sodium salt in the infusion solutions tested is chemically and physically stable for at least 2 days at room temperature and 5 days under refrigeration.
Function
Esomeprazole sodium is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.
Specification
Test items |
Specifications |
Result |
Appearance |
White or slightly coloured powder,slight hygroscopic |
almost white powder |
Identification A. IR B.Enantiomeric purity C.Reaction of maganesium D. Water |
IR Conforms to the CRS.(2.2.24) Impurity F ≤0.2%(2.2.29) It gives reaction of magnesium(2.3.1) 6.2%~8.0%(2.5.12) |
Complies 0.05% Complies 7.3% |
Absorbance |
The absorbance is not greater than 0.20 at 440nm.(2.2.25) |
0.12 |
Related substances(HPLC) Impurity E Impurity D Unspecified impurities Total impurity Impurity F |
(2.2.29) ≤0.15% ≤0.15% ≤0.10% ≤0.3% ≤0.2%(2.2.29) |
0.04% 0.10% 0.03% 0.2% 0.05% |
Magnesium |
3.30%~3.55% |
3.46% |
Water by K.F. |
6.2%~8.0%(2.5.12) |
7.3% |
Assay(HPLC) |
98.0%~102.0%(2.2.29) |
99.9% |
Residual solvents: a) Acetne b)Etyl aetate c)Methylene chloide d)Methnol e)Toluee f)Benzene |
Not more than 5000ppm Not more than 5000ppm Not more than 100ppm Not more than 3000ppm Not more than 890ppm Not more than 2ppm |
3ppm Not detected Not detected 77ppm Not detected Not detected |
Product picture
Packing &shipping&Payment
Payment:T/T,,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms) | 1 - 10000 | >10000 |
Est. Time(days) | 5 | To be negotiated |
Advantage
In stock