Hebei Mojin Biotechnology Co.,Ltd
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CAS NO.1642288-47-8
comestic(1-22)Metric Toncomestic(1-22)Metric Ton
MYK-461 is a drug used to treat obstructive hypertrophic cardiomyopathy as a cardiac myosin inhibitor.
Mavacamten is used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy.
It is used to treat symptomatic obstructive hypertrophic cardiomyopathy (HCM).
Mavacamten（MYK-461）is a first-in-class allosteric inhibitor of cardiac myosin that promises to provide clinicians with targeted therapy for these patients.
It is a mechanistically novel small molecule that acts on the sarcolemma to specifically inhibit contractility and has been proposed as a treatment for HCM.
Product information
| CAS: | 1642288-47-8 |
| MF: | C15H19N3O2 |
| MW: | 273.33 |
| density | 1.19±0.1 g/cm3(Predicted) |
| solubility | insoluble in H2O; ≥11.32 mg/mL in EtOH with ultrasonic; ≥13.65 mg/mL in DMSO |
| form | solid |
| pka | 8.83±0.40(Predicted) |
| InChI | InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1 |
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