Hebei Mojin Biotechnology Co.,Ltd
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China (Mainland)
Business Type:Trading Company
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Ms.betty Ms.mayCAS NO.78628-80-5
medical (1-25)Kilogrammedical (25-1000)Kilogrampharmaceutical(1-25)Kilogram
Our company have high quality product , and also the product we have good manufacture .
First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried out for one month.Besides，this type has a good viscosity. the prouct can make Gel hand sanitizer thickener cosmetics industry.
We can ensure the product quality , If the product is not satisfactory, you can return it at any time.
In the chemical industry, the process of producing a chemical product. Including raw material pretreatment, reactant chemical reaction and chemical product separation purification, final packaging sales.
our product have resonable price and good service high quality and inexpensive, you deserve.every webiste we have the sales point, your purchase is convenient.
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Product Name: Terbinafine Hydrochloride
Purity: 98%min
Appearance: White crystalline powder
CAS No.: 78628-80-5
EINECS: 245-385-8
Molecular formula: C21H25N·HCl
Molecular weight: 327.9
Terbinafine·HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis.
Additionally, Terbinafine has also been reported to suppress cell proliferation in vitro and in vivo through inhibition of DNA synthesis and apoptosis activation. It has also been noted that by pretreating of cells with a p21 specific antisense oligonucleotide the Terbinafine induced inhibition of cell growth can be reversed.
Certification of analysis
|
Items |
Specifications |
Results |
|
Characters |
|
|
|
Appearance |
White or off-white crystalline powder |
White powder |
|
Solubility |
Practically insoluble in water and in aceton, soluble in ethanol and in methanol |
Complies |
|
Identification |
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|
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A: IR |
The infrared absorption spectrum exhibits maximum only at the same wavelengths as that of the standard sample |
Complies |
|
B: |
It gives reaction of chlorides |
Complies |
|
|
Impurity A NMT 0.1% |
0.00% |
|
|
Impurity B NMT 0.1% |
0.01% |
|
|
Impurity C NMT 0.1% |
0.02% |
|
|
Impurity D NMT 0.1% |
0.02% |
|
|
Any other impurity NMT0.1% |
0.05% |
|
|
Total of impurity NMT 0.3% |
0.15% |
|
Loss on drying |
NMT0.5% |
0.15% |
|
Sulphated ash |
NMT0.1% |
0.02% |
|
Assay |
99%~101% (dried substance ) |
99.85% |
Function
Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.
Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water.
Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.