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Hebei Mujin Biotechnology Co.,Ltd

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V-9-M cholecystokinin nonapeptide

CAS NO.99291-20-0

  • Min.Order: 1 Kilogram
  • Payment Terms: T/T
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Product Details

Keywords

  • Smeglutide
  • L-α-aspartyl-L-prolyl-L-methionine
  • L-alanyl-L-valyl-L-α-aspartyl-L-prolyl-

Quick Details

  • ProName: V-9-M cholecystokinin nonapeptide
  • CasNo: 99291-20-0
  • Molecular Formula: C42H69N9O14S
  • Appearance: white powder
  • Application: V-9-M Cholecystokinin nonapeptide is ...
  • DeliveryTime: 3-7 days
  • PackAge: In barrels and bags
  • Port: tianjin
  • ProductionCapacity: 10000 Kilogram/Month
  • Purity: 99
  • Storage: Dry and wet
  • Transportation: by air or by sea or by express
  • LimitNum: 1 Kilogram
  • Grade: Industrial Grade

Superiority

1. Rich experience.Having been specialized in this field for years, we have rich experience and widespread sales network around the word. Our hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. We are not got good feedback from our guest, but also established long business relationship with them. 
  
2. Great quality and high purity.Good quality is one secret for our success. All of our products enjoys high purity. Thus, it can make sure our client's need. Welcome order the samples, MOQ just 10 grams. 
 
3. Safest and fastest delivery.We have mass stock, so that we can arrange the delivery within 24hours once receiving the payment. Tracking number would be informed quickly after shipment. We have our own way of packing which could ship 0.01 kilo to 50 kilo products a time. 
 
4. Good after-sales service.24/7 is available. We will tell you the package updated info ASAP. And try our best to solve various problems customers encountered! 
 
5. Experiential shopping


Our Advantages
1.Own chemical factory

2.Abundant professional production experience

3.Sample is free of charge and in stock with fast delivery

4. Price,quality & service, we care that all you cares

5. Prompt reply keep in touch to save your times

6.Easily customs clearance, we're very good to all these controls

7.Dedicated researchers to make your customization.
 

Details

CAS: 99291-20-0
MF: C42H69N9O14S
MW: 956.11
EINECS:  
Product Categories: Peptide;99291-20-0
Mol File: 99291-20-0.mol
V-9-M cholecystokinin nonapeptide Structure
 
V-9-M cholecystokinin nonapeptide Chemical Properties
Boiling point  1350.7±65.0 °C(Predicted)
density  1.306±0.06 g/cm3(Predicted)
pka 3.51±0.10(Predicted)
InChIKey AIKMAJWJXJPJNB-HNRKYVDVNA-N
V-9-M cholecystokinin nonapeptide Usage And Synthesis
Description V-9-M Cholecystokinin nonapeptide is a glucagon-like peptide receptor agonist, namely GLP-1 receptor agonist. Human GLP-1 is a peptide hormone secreted by intestinal L cells. Cholecystokinin Precursor (24-32), rat has apparent sedative actions and prevents experimental amnesisa in rats.
Uses V-9-M cholecystokinin nonapeptide belongs to the glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist) class of hypoglycemic drugs, which increase insulin secretion in a glucose-dependent manner and inhibit glucagon secretion , and can promote gastric emptying, centrally suppress appetite, reduce food intake, and then reduce glucose absorption to achieve the effect of lowering blood sugar.
Mechanism of action V-9-M cholecystokinin nonapeptide's mechanism of action is to act on islet beta cells, promote the synthesis and secretion of insulin, stimulate the proliferation and differentiation of islet beta cells, inhibit the apoptosis of islet beta cells, increase the number of islet beta cells, and protect islet function. It can also act on islet alpha cells, inhibit the release of glucagon, and reduce the release of hepatic glucose.
References 1. Takashima A, Itoh S. Neuropharmacological properties of V-9-M, a putative neuropeptide derived from procholecystokinin, in the rat. Can J Physiol Pharmacol. 1989 Mar;67(3):223-7. DOI: 10.1016/0301-0082(90)90035-F
2. Cholecytokinin (CCK) gene-related peptides: distribution and characterization of immunoreactive pro-CCK and an amino-terminal pro-CCK fragment in rat brain. DOI: 10.1016/0006-8993(85)90813-3
3. Cao G, Beinfeld MC. Calcium-dependent pro-cholecystokinin V-9-M immunoreactive peptide release from rat brain slices and CCK-secreting rat medullary thyroid carcinoma cells in culture. Peptides. 1992 Nov-Dec;13(6):1087-90. DOI: 10.1016/0196-9781(92)90011-Q